A collaborative research group led by Kyoto University and Nagoya City University demonstrated that smartphone-delivered cognitive behavioral therapy can prevent the onset of major depression over a one-year period among individuals with subthreshold depression. The study also became the first in the world to evaluate the long-term “Total Burden of Depression.” The results were published in the British Journal of Psychiatry and were accompanied by a press release.

Paper link: https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/cognitive-and-behavioural-skills-to-prevent-major-depression-among-adults-with-subthreshold-depression-50week-followup-analysis-of-smartphone-cbt-randomised-trials-resilient-trial/C4D285AD1072A78996DE06633442C1F3

Press release (Japanese): https://www.kyoto-u.ac.jp/ja/research-news/2026-06-01